Emerging into the death metal scene in 1987 from Florida, USA under the name of Amon, they quickly became one of the most successful Death Metal bands of all time. After releasing two demos as "Amon," they changed their name to Deicide in 1990 and released their self-titled album shortly afterwards.

Only two original members of the band remain: Glen Benton (bass/vocals)and Steve Asheim (drums)

Glen Benton, whose controversial lyrics cover such topics as Satan and death, showed his hatred for Christianity by pressing a red-hot inverted cross to his forehead until his skin scarred in that shape.

The manner of Glen Benton's anti-christianity has been a matter of debate for Deicide fans even from the early days of the band. It seems that in the first three albums -"Deicide" (1990), "Legion" (1993) and "Once Upon the Cross" (1995) - Benton's Satanism resembled a cult, making use of sacrificial elements in the lyrics and calling upon the demons of the Christian myths. Since "Serpents of the Light" released in 1997, a more sophisticated form of Satanism has been noted - focusing instead on mankind's potential for advancement.

Deicide have released seven full-length albums thus far, plus a live album and a DVD, and are currently still active on Earache records.

Deicide's latest anslaut on Christanity release "Stench of the Redemption was released in 2006.

On May 24, 2007, Deicide Parted Ways With Ralph Santolla.